There is no single answer but, in my opinion, you should choose based on what your dependencies use.
For example, with Bootstrap 4, the team are moving to SASS. If you use SASS, you can include their SASS sources instead of serving the pre-made Bootstrap 4 .css files - this gives you all sorts of power to override variables that affect Bootstrap or to pick and choose parts of Bootstrap to include or to @extend Bootstrap classes in your own CSS rules.
With respect to your question about Dreamweaver integration: never pick your tech. based on your tools. Pick your tools to work with the tech. you judge to be best.